Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model

BACKGROUND: Myocardial injury is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). This study aimed to test the hypothesis that melatonin could attenuate myocardial injury in a rat CPB model. METHODS: Eighteen male Sprague-Dawley rats were randomly divided into three g...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Huang, Xiaolin, Hou, Jian, Huang, Suiqing, Feng, Kangni, Yue, Yuan, Li, Huayang, Huang, Shaojie, Liang, Mengya, Chen, Guangxian, Wu, Zhongkai
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053380/
https://ncbi.nlm.nih.gov/pubmed/33954056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11264
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