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A 4-gene-based hypoxia signature is associated with tumor immune microenvironment and predicts the prognosis of pancreatic cancer patients

BACKGROUND: Pancreatic cancer (PAC) is one of the most devastating cancer types with an extremely poor prognosis, characterized by a hypoxic microenvironment and resistance to most therapeutic drugs. Hypoxia has been found to be one of the factors contributing to chemoresistance in PAC, but also a m...

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Pubblicato in:World J Surg Oncol
Autori principali: Ding, Jianfeng, He, Xiaobo, Cheng, Xiao, Cao, Guodong, Chen, Bo, Chen, Sihan, Xiong, Maoming
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053300/
https://ncbi.nlm.nih.gov/pubmed/33865399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-021-02204-7
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