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Computing Absolute Free Energy with Deep Generative Models

Fast and accurate evaluation of free energy has broad applications from drug design to material engineering. Computing the absolute free energy is of particular interest since it allows the assessment of the relative stability between states without intermediates. Here we introduce a general framewo...

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Vydáno v:J Phys Chem B
Hlavní autoři: Ding, Xinqiang, Zhang, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053255/
https://ncbi.nlm.nih.gov/pubmed/33143418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c08645
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