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Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients

Multiple driver genes in individual patient samples may cause resistance to individual drugs in precision medicine. However, current computational methods have not studied how to fill the gap between personalized driver gene identification and combinatorial drug discovery for individual patients. He...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Guo, Wei-Feng, Zhang, Shao-Wu, Feng, Yue-Hua, Liang, Jing, Zeng, Tao, Chen, Luonan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053130/
https://ncbi.nlm.nih.gov/pubmed/33434272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1272
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