A ProQ/FinO family protein involved in plasmid copy number control favours fitness of bacteria carrying mcr-1-bearing IncI2 plasmids

The plasmid-encoded colistin resistance gene mcr-1 challenges the use of polymyxins and poses a threat to public health. Although IncI2-type plasmids are the most common vector for spreading the mcr-1 gene, the mechanisms by which these plasmids adapt to host bacteria and maintain resistance genes r...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Yang, Jun, Wang, Hai-Hong, Lu, Yaoyao, Yi, Ling-Xian, Deng, Yinyue, Lv, Luchao, Burrus, Vincent, Liu, Jian-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053102/
https://ncbi.nlm.nih.gov/pubmed/33721023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab149
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