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Bok binds to a largely disordered loop in the coupling domain of type 1 inositol 1,4,5-trisphosphate receptor
Bcl-2-related ovarian killer (Bok) binds tightly to inositol 1,4,5-trisphosphate receptors (IP(3)RS). To better understand this interaction, we sought to elucidate the Bok binding determinants in IP(3)R1, focusing on the ~ 75 amino acid loop (residues 1882-1957) between α helices 72 and 73. Bioinfor...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052301/ https://ncbi.nlm.nih.gov/pubmed/33773141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.03.047 |
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