Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial

Staphylococcus aureus colonizes patients with atopic dermatitis (AD) and exacerbates disease by promoting inflammation. The present study investigated the safety and mechanisms of action of Staphylococcus hominis A9 (ShA9), a bacterium isolated from healthy human skin, as a topical therapy for AD. S...

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Publicat a:Nat Med
Autors principals: Nakatsuji, Teruaki, Hata, Tissa R., Tong, Yun, Cheng, Joyce Y., Shafiq, Faiza, Butcher, Anna M., Salem, Secilia S., Brinton, Samantha L., Spergel, Amanda K. Rudman, Johnson, Keli, Jepson, Brett, Calatroni, Agustin, David, Gloria, Ramirez-Gama, Marco, Taylor, Patricia, Leung, Donald Y. M., Gallo, Richard L.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052297/
https://ncbi.nlm.nih.gov/pubmed/33619370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-021-01256-2
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