Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells

Endoplasmic reticulum (ER) plays a key role in the folding, modification, and trafficking of proteins. When the homeostasis of the ER is disturbed, un/misfolded proteins accumulate in the ER which leads to ER stress. Sustained ER stress results in apoptosis, which is associated with various diseases...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Naresh Amin, Karan, Rajagru, Palanisamy, Sarkar, Koustav, Ganesh, M. R., Suzuki, Takayoshi, Ali, Daoud, Kunka Mohanram, Ramkumar
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052152/
https://ncbi.nlm.nih.gov/pubmed/33897939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/2732435
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