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Significant association between host transcriptome-derived HPV oncogene E6* influence score and carcinogenic pathways, tumor size, and survival in head and neck cancer

BACKGROUND: Human papillomavirus (HPV) oncogenes E6, E7 and shorter isoforms of E6 (E6*) are known carcinogenic factors in head and neck squamous cell carcinoma (HNSCC). Little is known regarding E6* functions. METHODS: We analyzed RNA-seq data from 68 HNSCC HPV type 16-positive tumors to determine...

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Publicado no:Head Neck
Main Authors: Qin, Tingting, Koneva, Lada A., Liu, Yidan, Zhang, Yanxiao, Arthur, Anna E., Zarins, Katie R., Carey, Thomas E, Chepeha, Douglas, Wolf, Gregory T., Rozek, Laura S., Sartor, Maureen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052131/
https://ncbi.nlm.nih.gov/pubmed/32406560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.26244
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