Lenvatinib prevents liver fibrosis by inhibiting hepatic stellate cell activation and sinusoidal capillarization in experimental liver fibrosis

Molecular targeted agents are pharmacologically used to treat liver fibrosis and have gained increased attention. The present study examined the preventive effect of lenvatinib on experimental liver fibrosis and sinusoidal capillarization as well as the in vitro phenotypes of hepatic stellate cells....

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Ogawa, Hiroyuki, Kaji, Kosuke, Nishimura, Norihisa, Takagi, Hirotetsu, Ishida, Koji, Takaya, Hiroaki, Kawaratani, Hideto, Moriya, Kei, Namisaki, Tadashi, Akahane, Takemi, Yoshiji, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051749/
https://ncbi.nlm.nih.gov/pubmed/33609067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16363
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