Lenvatinib prevents liver fibrosis by inhibiting hepatic stellate cell activation and sinusoidal capillarization in experimental liver fibrosis

Molecular targeted agents are pharmacologically used to treat liver fibrosis and have gained increased attention. The present study examined the preventive effect of lenvatinib on experimental liver fibrosis and sinusoidal capillarization as well as the in vitro phenotypes of hepatic stellate cells....

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Vydáno v:J Cell Mol Med
Hlavní autoři: Ogawa, Hiroyuki, Kaji, Kosuke, Nishimura, Norihisa, Takagi, Hirotetsu, Ishida, Koji, Takaya, Hiroaki, Kawaratani, Hideto, Moriya, Kei, Namisaki, Tadashi, Akahane, Takemi, Yoshiji, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051749/
https://ncbi.nlm.nih.gov/pubmed/33609067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16363
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