Prognostic impact of early tumor shrinkage and depth of response in patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors

BACKGROUND: Immune checkpoint inhibitors (ICIs) are the new standard of care in microsatellite instability-high (MSI-H)/deficient mismatch repair (dMMR) metastatic colorectal cancer (mCRC). Since tumor response dynamic parameters already shown a strong association with survival outcomes in patients...

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Publicado en:J Immunother Cancer
Main Authors: Fucà, Giovanni, Corti, Francesca, Ambrosini, Margherita, Intini, Rossana, Salati, Massimiliano, Fenocchio, Elisabetta, Manca, Paolo, Manai, Chiara, Daniel, Francesca, Raimondi, Alessandra, Morano, Federica, Corallo, Salvatore, Prisciandaro, Michele, Spallanzani, Andrea, Quarà, Virginia, Belli, Carmen, Vaiani, Marta, Curigliano, Giuseppe, Cremolini, Chiara, De Braud, Filippo, Di Bartolomeo, Maria, Zagonel, Vittorina, Lonardi, Sara, Pietrantonio, Filippo
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2021
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051394/
https://ncbi.nlm.nih.gov/pubmed/33849927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-002501
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