The macrophage stimulating anti-cancer agent, RRx-001, protects against ischemia-reperfusion injury

BACKGROUND: RRx-001, a clinical macrophage-stimulating anti-cancer agent that also produces nitric oxide (NO) was studied in a model of ischemia-reperfusion injury. METHODS: The production of NO is dependent on the oxygen tension because nitric oxide synthases convert l-arginine to NO and l-citrulli...

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Publicado en:Expert Rev Hematol
Autores principales: Cabrales, Pedro, Caroen, Scott, Oronsky, Arnold, Carter, Corey, Trepel, Jane, Summers, Thomas, Reid, Tony, Oronsky, Neil, Lybeck, Michelle, Oronsky, Bryan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051333/
https://ncbi.nlm.nih.gov/pubmed/28448172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17474086.2017.1324779
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