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HIV-1 genomic RNA U3 region forms a stable quadruplex-hairpin structure

The U3 promoter region of the HIV-1 long terminal repeat (LTR) has previously been shown to fold into a series of dynamic G-quadruplex structures. Among the G-quadruplexes identified in the LTR sequence, LTR-III was shown to be the most stable in vitro. NMR studies of this 28-nucleotide (nt) DNA rev...

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Publicat a:Biophys Chem
Autors principals: Harpster, Chelsea, Boyle, Elaina, Musier-Forsyth, Karin, Kankia, Besik
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051326/
https://ncbi.nlm.nih.gov/pubmed/33713997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2021.106567
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