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RNA Peach and Mango: orthogonal two-color fluorogenic aptamers distinguish nearly identical ligands

Two-channel fluorogenic RNA aptamer-based imaging is currently challenging. While we have previously characterized the Mango series of aptamers that bind tightly and specifically to the green fluorophore TO1-Biotin, the next aim was to identify an effective fluorogenic aptamer partner for two-color...

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Foilsithe in:RNA
Main Authors: Kong, Kristen Y.S., Jeng, Sunny C.Y., Rayyan, Batool, Unrau, Peter J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051271/
https://ncbi.nlm.nih.gov/pubmed/33674421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.078493.120
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