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Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures

The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including chronic obstructive pulmonary disease (COPD) due to the complex microenvironment in lungs and the plasticity of macrophages. We examined macrophage sub-phenotypes in bronchoalveolar lavage (BAL)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takiguchi, Hiroto, Yang, Chen X., Yang, Cheng Wei Tony, Sahin, Basak, Whalen, Beth A., Milne, Stephen, Akata, Kentaro, Yamasaki, Kei, Yang, Julia Shun Wei, Cheung, Chung Yan, Vander Werff, Ryan, McNagny, Kelly M., Leitao Filho, Fernando Sergio, Shaipanich, Tawimas, van Eeden, Stephan F., Obeidat, Ma’en, Leung, Janice M., Sin, Don D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050093/
https://ncbi.nlm.nih.gov/pubmed/33859282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87720-y
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