Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets

Determining the epigenetic program that generates unique cell types in the kidney is critical for understanding cell-type heterogeneity during tissue homeostasis and injury response. Here, we profile open chromatin and gene expression in developing and adult mouse kidneys at single cell resolution....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Miao, Zhen, Balzer, Michael S., Ma, Ziyuan, Liu, Hongbo, Wu, Junnan, Shrestha, Rojesh, Aranyi, Tamas, Kwan, Amy, Kondo, Ayano, Pontoglio, Marco, Kim, Junhyong, Li, Mingyao, Kaestner, Klaus H., Susztak, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050063/
https://ncbi.nlm.nih.gov/pubmed/33859189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22266-1
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