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Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets

Determining the epigenetic program that generates unique cell types in the kidney is critical for understanding cell-type heterogeneity during tissue homeostasis and injury response. Here, we profile open chromatin and gene expression in developing and adult mouse kidneys at single cell resolution....

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Miao, Zhen, Balzer, Michael S., Ma, Ziyuan, Liu, Hongbo, Wu, Junnan, Shrestha, Rojesh, Aranyi, Tamas, Kwan, Amy, Kondo, Ayano, Pontoglio, Marco, Kim, Junhyong, Li, Mingyao, Kaestner, Klaus H., Susztak, Katalin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050063/
https://ncbi.nlm.nih.gov/pubmed/33859189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22266-1
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