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Transcriptional changes and preservation of bone mass in hibernating black bears

Physical inactivity leads to losses of bone mass and strength in most mammalian species. In contrast, hibernating bears show no bone loss over the prolonged periods (4–6 months) of immobility during winter, which suggests that they have adaptive mechanisms to preserve bone mass. To identify transcri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Goropashnaya, Anna V., Tøien, Øivind, Ramaraj, Thiruvarangan, Sundararajan, Anitha, Schilkey, Faye D., Barnes, Brian M., Donahue, Seth W., Fedorov, Vadim B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050052/
https://ncbi.nlm.nih.gov/pubmed/33859306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87785-9
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