Quantification of Macrophage-Driven Inflammation During Myocardial Infarction with (18)F-LW223, a Novel TSPO Radiotracer with Binding Independent of the rs6971 Human Polymorphism

Myocardial infarction (MI) is one of the leading causes of death worldwide, and inflammation is central to tissue response and patient outcomes. The 18-kDa translocator protein (TSPO) has been used in PET as an inflammatory biomarker. The aims of this study were to screen novel, fluorinated, TSPO ra...

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Publicado en:J Nucl Med
Main Authors: MacAskill, Mark G., Stadulyte, Agne, Williams, Lewis, Morgan, Timaeus E.F., Sloan, Nikki L., Alcaide-Corral, Carlos J., Walton, Tashfeen, Wimberley, Catriona, McKenzie, Chris-Anne, Spath, Nick, Mungall, William, BouHaidar, Ralph, Dweck, Marc R., Gray, Gillian A., Newby, David E., Lucatelli, Christophe, Sutherland, Andrew, Pimlott, Sally L., Tavares, Adriana A.S.
Formato: Artigo
Idioma:Inglês
Publicado: Society of Nuclear Medicine 2021
Assuntos:
Cardiovascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049364/
https://ncbi.nlm.nih.gov/pubmed/32859708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.243600
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