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Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins

Human ORP3 belongs to the oxysterol-binding protein (OSBP) family of lipid transfer proteins and is involved in lipid trafficking and cell signaling. ORP3 localizes to the ER-PM interfaces and is implicated in lipid transport and focal adhesion dynamics. Here, we report the 2.6–2.7 Å structures of t...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Tong, Junsen, Tan, Lingchen, Im, Young Jun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049286/
https://ncbi.nlm.nih.gov/pubmed/33857182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248781
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