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Nanoscale Amperometry Reveals that Only a Fraction of Vesicular Serotonin Content is Released During Exocytosis from Beta Cells

Recent work has shown that chemical release during the fundamental cellular process of exocytosis in model cell lines is not all‐or‐none. We tested this theory for vesicular release from single pancreatic beta cells. The vesicles in these cells release insulin, but also serotonin, which is detectibl...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Hatamie, Amir, Ren, Lin, Dou, Haiqiang, Gandasi, Nikhil R., Rorsman, Patrik, Ewing, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049002/
https://ncbi.nlm.nih.gov/pubmed/33340209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202015902
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