Exome Sequencing of 21 Bardet‐Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians

OBJECTIVE: In an ongoing effort to identify the genetic variation that contributes to obesity in American Indians, known Bardet–Biedl syndrome (BBS) genes were analyzed for an effect on BMI and leptin signaling. METHODS: Potentially deleterious variants (Combined Annotation Dependent Depletion score...

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Publié dans:Obesity (Silver Spring)
Auteurs principaux: Day, Samantha E., Muller, Yunhua L., Koroglu, Cigdem, Kobes, Sayuko, Wiedrich, Kim, Mahkee, Darin, Kim, Hye In, Van Hout, Cris, Gosalia, Nehal, Ye, Bin, Shuldiner, Alan R., Knowler, William C., Hanson, Robert L., Bogardus, Clifton, Baier, Leslie J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
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Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048836/
https://ncbi.nlm.nih.gov/pubmed/33616283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.23115
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