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Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults

Rationale: Macrophages are the most abundant immune cell in the alveoli and small airways and are traditionally viewed as a homogeneous population during health. Whether distinct subsets of airspace macrophages are present in healthy humans is unknown. Single-cell RNA sequencing allows for examinati...

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Pubblicato in:Am J Respir Crit Care Med
Autori principali: Mould, Kara J., Moore, Camille M., McManus, Shannon A., McCubbrey, Alexandra L., McClendon, Jazalle D., Griesmer, Christine L., Henson, Peter M., Janssen, William J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048748/
https://ncbi.nlm.nih.gov/pubmed/33079572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202005-1989OC
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