Anti‐β2‐glycoprotein I and anti‐prothrombin antibodies cause lupus anticoagulant through different mechanisms of action

BACKGROUND: The presence of lupus anticoagulant (LA) is an independent risk factor for thrombosis. This laboratory phenomenon is detected as a phospholipid‐dependent prolongation of the clotting time and is caused by autoantibodies against beta2‐glycoprotein I (β2GPI) or prothrombin. How these autoa...

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Veröffentlicht in:J Thromb Haemost
Hauptverfasser: Noordermeer, Tessa, Molhoek, Jessica E., Schutgens, Roger E. G., Sebastian, Silvie A. E., Drost‐Verhoef, Sandra, van Wesel, Annet C. W., de Groot, Philip G., Meijers, Joost C. M., Urbanus, Rolf T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Thrombosis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048633/
https://ncbi.nlm.nih.gov/pubmed/33421291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15241
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