Characterization of alcohol polygenic risk scores in the context of mental health outcomes: Within-individual and intergenerational analyses in the Avon Longitudinal Study of Parents and Children

BACKGROUND: Heavy alcohol consumption often co-occurs with mental health problems; this could be due to confounding, shared biological mechanisms, or causal effects. Polygenic risk scores (PRS) for alcohol use can be used to explore this association at critical life stages. DESIGN: We characterized...

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Pubblicato in:Drug Alcohol Depend
Autori principali: Easey, Kayleigh E., Wootton, Robyn E., Sallis, Hannah M., Haan, Elis, Schellhas, Laura, Munafò, Marcus R., Timpson, Nicholas J., Zuccolo, Luisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047864/
https://ncbi.nlm.nih.gov/pubmed/33676074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2021.108654
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