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Identification of Bioactive SNM1A Inhibitors

[Image: see text] SNM1A is a nuclease required to repair DNA interstrand cross-links (ICLs) caused by some anticancer compounds, including cisplatin. Unlike other nucleases involved in ICL repair, SNM1A is not needed to restore other forms of DNA damage. As such, SNM1A is an attractive target for se...

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Foilsithe in:ACS Omega
Main Authors: Buzon, Beverlee, Grainger, Ryan A., Rzadki, Cameron, Huang, Simon York Ming, Junop, Murray
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2021
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047731/
https://ncbi.nlm.nih.gov/pubmed/33869915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03528
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