Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress

Rationale: The myosin light chain kinase gene, MYLK, encodes three proteins via unique promoters, including the non-muscle isoform of myosin light chain kinase (nmMLCK), a cytoskeletal protein centrally involved in regulation of vascular integrity. As MYLK coding SNPs are associated with severe infl...

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Detalhes bibliográficos
Publicado no:Clin Sci (Lond)
Main Authors: Sun, Xiaoguang, Sun, Belinda L., Sammani, Saad, Bermudez, Tadeo, Dudek, Steven M., Camp, Sara M., Garcia, Joe G.N.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047480/
https://ncbi.nlm.nih.gov/pubmed/33792658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20201448
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