One Stone, Two Birds: The Roles of Tim-3 in Acute Myeloid Leukemia

T cell immunoglobulin and mucin protein 3 (Tim-3) is an immune checkpoint and plays a vital role in immune responses during acute myeloid leukemia (AML). Targeting Tim-3 kills two birds with one stone by balancing the immune system and eliminating leukemia stem cells (LSCs) in AML. These functions m...

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Udgivet i:Front Immunol
Main Authors: Wang, Zhiding, Chen, Jinghong, Wang, Mengzhen, Zhang, Linlin, Yu, Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047468/
https://ncbi.nlm.nih.gov/pubmed/33868234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.618710
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