The Degradation of Airway Epithelial Tight Junctions in Asthma Under High Airway Pressure Is Probably Mediated by Piezo-1

Full functioning of the airway physical barrier depends on cellular integrity, which is coordinated by a series of tight junction (TJ) proteins. Due to airway spasm, edema, and mucus obstruction, positive end-expiratory alveolar pressure (also termed auto-PEEP) is a common pathophysiological phenome...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Zhou, Jia, Zhou, Xiang-dong, Xu, Rui, Du, Xian-zhi, Li, Qi, Li, Bin, Zhang, Guo-yue, Chen, Ling-xiu, Perelman, Juliy M., Kolosov, Victor P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047413/
https://ncbi.nlm.nih.gov/pubmed/33868003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.637790
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