Multigenerational Epigenetic Regulation of Allergic Diseases: Utilizing an Experimental Dust Mite-Induced Asthma Model

Environmental exposures have been linked to increased asthma risk, particularly during pregnancy and in early life. Here we use a mouse model of allergic lung disease to examine the effects of pre- and perinatal house dust mite (HDM) allergen exposure on offspring phenotypic and transcriptional outc...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Pulczinski, Jairus C., Shang, Yan, Dao, Tyna, Limjunyawong, Nathachit, Sun, Qinying, Mitzner, Wayne, Cheng, Robert YS, Tang, Wan-yee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047068/
https://ncbi.nlm.nih.gov/pubmed/33868365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.624561
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