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Optimisation of a PC12 cell-based in vitro stroke model for screening neuroprotective agents

Stroke causes death and disability globally but no neuroprotectant is approved for post-stroke neuronal injury. Neuroprotective compounds can be identified using oxygen glucose deprivation (OGD) of neuronal cells as an in vitro stroke model. Nerve growth factor (NGF)-differentiated PC12 pheochromocy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chua, PinFen, Lim, William K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046774/
https://ncbi.nlm.nih.gov/pubmed/33854099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87431-4
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