Bioinformatics and In Vitro Studies Reveal the Importance of p53, PPARG and Notch Signaling Pathway in Inhibition of Breast Cancer Stem Cells by Hesperetin

Purpose: The failure of chemotherapy in breast cancer is caused by breast cancer stem cells (BCSCs), a minor population of cells in bulk mammary tumors. Previously, hesperetin, a citrus flavonoid, showed cytotoxicity in several cancer cells and increased cytotoxicity of doxorubicin and cisplatin. He...

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Dettagli Bibliografici
Pubblicato in:Adv Pharm Bull
Autori principali: Hermawan, Adam, Ikawati, Muthi, Khumaira, Annisa, Putri, Herwandhani, Jenie, Riris Istighfari, Angraini, Sonia Meta, Muflikhasari, Haruma Anggraini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Tabriz University of Medical Sciences 2021
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046396/
https://ncbi.nlm.nih.gov/pubmed/33880358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.34172/apb.2021.033
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