Major Histocompatibility Complex Class I-Related Chain A (MICA) Allelic Variants Associate With Susceptibility and Prognosis of Gastric Cancer

Gastric cancer (GC) is the fifth most prevalent type of cancer worldwide. Gastric tumor cells express MICA protein, a ligand to NKG2D receptor that triggers natural killer (NK) cells effector functions for early tumor elimination. MICA gene is highly polymorphic, thus originating alleles that encode...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Toledo-Stuardo, Karen, Ribeiro, Carolina H., Canals, Andrea, Morales, Marcela, Gárate, Valentina, Rodríguez-Siza, Jose, Tello, Samantha, Bustamante, Marco, Armisen, Ricardo, Matthies, Douglas J., Zapata-Torres, Gerald, González-Hormazabal, Patricio, Molina, María Carmen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045969/
https://ncbi.nlm.nih.gov/pubmed/33868281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.645528
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