A fish with no sex: gonadal and adrenal functions partition between zebrafish NR5A1 co-orthologs

People with NR5A1 mutations experience testicular dysgenesis, ovotestes, or adrenal insufficiency, but we do not completely understand the origin of this phenotypic diversity. NR5A1 is expressed in gonadal soma precursor cells before expression of the sex-determining gene SRY. Many fish have two co-...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Yan, Yi-Lin, Titus, Tom, Desvignes, Thomas, BreMiller, Ruth, Batzel, Peter, Sydes, Jason, Farnsworth, Dylan, Dillon, Danielle, Wegner, Jeremy, Phillips, Jennifer B, Peirce, Judy, Dowd, John, Buck, Charles Loren, Miller, Adam, Westerfield, Monte, Postlethwait, John H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045690/
https://ncbi.nlm.nih.gov/pubmed/33724412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyaa030
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