An expanded auxin-inducible degron toolkit for Caenorhabditis elegans

The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally deplete proteins in a range of organisms and cell types. Here, we describe a toolkit to augment the use of the AID system in Caenorhabditis elegans. We have generated a set of single-copy, tissue-specific (germli...

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Détails bibliographiques
Publié dans:Genetics
Auteurs principaux: Ashley, Guinevere E, Duong, Tam, Levenson, Max T, Martinez, Michael A Q, Johnson, Londen C, Hibshman, Jonathan D, Saeger, Hannah N, Palmisano, Nicholas J, Doonan, Ryan, Martinez-Mendez, Raquel, Davidson, Brittany R, Zhang, Wan, Ragle, James Matthew, Medwig-Kinney, Taylor N, Sirota, Sydney S, Goldstein, Bob, Matus, David Q, Dickinson, Daniel J, Reiner, David J, Ward, Jordan D
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Investigation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045686/
https://ncbi.nlm.nih.gov/pubmed/33677541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyab006
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