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Characterization of novel and large fragment deletions in exon 1 of the IL10RA gene in Chinese children with very early onset inflammatory bowel diseases

BACKGROUND: Defects in interleukin 10 (IL10) and its receptors are particularly involved in very early onset inflammatory bowel disease (VEOIBD). However, large fragment deletions of IL10 receptor A (IL10RA) are rare. METHODS: VEOIBD patients with confirmed mutations in the IL10RA gene were enrolled...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Tang, Zifei, Zhang, Ping, Ji, Min, Yin, Chunlan, Zhao, Ruiqin, Huang, Zhiheng, Huang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045347/
https://ncbi.nlm.nih.gov/pubmed/33849446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-021-01756-y
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