Impact of copy number variant and single nucleotide polymorphism of the programmed death-ligand 1 gene, programmed death-ligand 1 protein expression and therapy regimens on overall survival in a large group of Caucasian patients with non-small cell lung carcinoma

Anti-programmed death-1 or anti-programmed death-ligand 1 (PD-L1) blockade may be ineffective in some patients with non-small cell lung cancer (NSCLC) with high percentage of tumor cells with PD-L1 expression. In addition, immunotherapy may provide great benefits in patients without PD-L1 expression...

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Vydáno v:Oncol Lett
Hlavní autoři: Grenda, Anna, Krawczyk, Paweł, Kucharczyk, Tomasz, Błach, Justyna, Reszka, Katarzyna, Chmielewska, Izabela, Buczkowski, Jarosław, Kieszko, Robert, Siwiec, Jan, Kubiatowski, Tomasz, Bożyk, Aleksandra, Krukowska, Kinga, Jarosz, Bożena, Paśnik, Iwona, Pankowski, Juliusz, Świniuch, Daria, Stencel, Katarzyna, Gil, Michał, Lew, Kinga, Ramlau, Rodryg, Szczęsna, Aleksandra, Fidler, Sebastian, Sieracki, Andrzej, Każarnowicz, Andrzej, Serwatowski, Piotr, Grodzki, Tomasz, Milanowski, Janusz
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2021
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045160/
https://ncbi.nlm.nih.gov/pubmed/33868487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12710
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