Human Wharton’s Jelly Stem Cell Secretions Inhibit Human Leukemic Cell Line K562 in vitro by Inducing Cell Cycle Arrest and Apoptosis

Emerging resistance to the tyrosine kinase inhibitors that target the BCR-ABL1 oncoprotein has prompted research for novel therapeutics against chronic myeloid leukemia (CML). Herein, we evaluated the tumor inhibitory properties of the human Wharton’s jelly stem cells (hWJSCs) co-culture (hWJSC-CC)...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Huwaikem, Muneerah A. H., Kalamegam, Gauthaman, Alrefaei, Ghadeer, Ahmed, Farid, Kadam, Roaa, Qadah, Talal, Sait, Khalid H. W., Pushparaj, Peter N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044948/
https://ncbi.nlm.nih.gov/pubmed/33869169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.614988
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