Inflammatory Responses to Monomeric and Aggregated α-Synuclein in Peripheral Blood of Parkinson Disease Patients

To investigate whether different forms of α-synuclein (α-syn) proteins can induce inflammation and activate the NLRP3 inflammasome, we stimulated with monomeric or aggregated α-syn peripheral blood mononuclear cells of Parkinson disease (PD) patients and age- and sex-matched healthy controls (HC). A...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Piancone, Federica, Saresella, Marina, La Rosa, Francesca, Marventano, Ivana, Meloni, Mario, Navarro, Jorge, Clerici, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044810/
https://ncbi.nlm.nih.gov/pubmed/33867921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.639646
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