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Role of interferon therapy in severe COVID-19: the COVIFERON randomized controlled trial

Type 1 Interferons (IFNs) have been associated with positive effects on Coronaviruses. Previous studies point towards the superior potency of IFNβ compared to IFNα against viral infections. We conducted a three-armed, individually-randomized, open-label, controlled trial of IFNβ1a and IFNβ1b, compar...

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Publicado en:Sci Rep
Main Authors: Alavi Darazam, Ilad, Shokouhi, Shervin, Pourhoseingholi, Mohamad Amin, Naghibi Irvani, Seyed Sina, Mokhtari, Majid, Shabani, Minoosh, Amirdosara, Mahdi, Torabinavid, Parham, Golmohammadi, Maryam, Hashemi, SayedPayam, Azimi, Arsalan, Jafarazadeh Maivan, Mohammad Hossein, Rezaei, Omidvar, Zali, Alireza, Hajiesmaeili, Mohammadreza, Shabanpour Dehbsneh, Hadiseh, Hoseyni Kusha, Akram, Taleb Shoushtari, Maryam, Khalili, Negar, Soleymaninia, Azam, Gachkar, Latif, Khoshkar, Ali
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044200/
https://ncbi.nlm.nih.gov/pubmed/33850184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86859-y
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