Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst forms

Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK treatment as monotherapy, but with a relative failure on drug bioavailability in the deep corneal stroma. The combination of chlorhexidine and propamidine isethionate is recommended in the current AK treatment. How...

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Publicado no:Sci Rep
Main Authors: Sangkanu, Suthinee, Mitsuwan, Watcharapong, Mahabusarakam, Wilawan, Jimoh, Tajudeen O., Wilairatana, Polrat, Girol, Ana Paula, Verma, Ajoy K., de Lourdes Pereira, Maria, Rahmatullah, Mohammed, Wiart, Christophe, Siyadatpanah, Abolghasem, Norouzi, Roghayeh, Mutombo, Polydor Ngoy, Nissapatorn, Veeranoot
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044166/
https://ncbi.nlm.nih.gov/pubmed/33850179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87381-x
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