GOLM1 restricts colitis and colon tumorigenesis by ensuring Notch signaling equilibrium in intestinal homeostasis

Intestinal epithelium serves as the first barrier against the infections and injuries that mediate colonic inflammation. Colorectal cancer is often accompanied with chronic inflammation. Differed from its well-known oncogenic role in many malignancies, we present here that Golgi membrane protein 1 (...

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Veröffentlicht in:Signal Transduct Target Ther
Hauptverfasser: Pu, Yang, Song, Ya, Zhang, Mengdi, Long, Caifeng, Li, Jie, Wang, Yanan, Xu, Yinzhe, Pan, Fei, Zhao, Na, Zhang, Xinyu, Xu, Yanan, Cui, Jianxin, Wang, Hongying, Li, Yan, Zhao, Yong, Jin, Di, Zhang, Hongbing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044123/
https://ncbi.nlm.nih.gov/pubmed/33850109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00535-1
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