Likelihood ratio statistics for gene set enrichment in Alzheimer’s disease pathways

INTRODUCTION: The study of Alzheimer’s disease (AD) has revealed biological pathways with implications for disease neuropathology and pathophysiology. Pathway-level effects may be mediated by covariates such as age or sex. METHODS: Gene set enrichment methods test hypotheses at the level of biologic...

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Publicado no:Alzheimers Dement
Main Authors: Bryan, Jordan, Mandan, Arpita, Kamat, Gauri, Gottschalk, W. Kirby, Badea, Alexandra, Adams, Kendra J., Thompson, J. Will, Colton, Carol A., Mukherjee, Sayan, Lutz, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044005/
https://ncbi.nlm.nih.gov/pubmed/33480182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12223
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