Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial

This analysis from the phase II BRIGHT AML 1003 trial reports the long-term efficacy and safety of glasdegib + low-dose cytarabine (LDAC) in patients with acute myeloid leukemia ineligible for intensive chemotherapy. The multicenter, open-label study randomized (2:1) patients to receive glasdegib +...

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Vydáno v:Ann Hematol
Hlavní autoři: Heuser, Michael, Smith, B. Douglas, Fiedler, Walter, Sekeres, Mikkael A., Montesinos, Pau, Leber, Brian, Merchant, Akil, Papayannidis, Cristina, Pérez-Simón, José A., Hoang, Caroline J., O’Brien, Thomas, Ma, Weidong Wendy, Zeremski, Mirjana, O’Connell, Ashleigh, Chan, Geoffrey, Cortes, Jorge E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2021
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043884/
https://ncbi.nlm.nih.gov/pubmed/33740113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-021-04465-4
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