Safety and Efficacy of Human Chorionic Gonadotropin Hormone-Derivative EA-230 in Cardiac Surgery Patients: A Randomized Double-Blind Placebo-Controlled Study

To determine the safety and efficacy of human chorionic gonadotropin hormone-derivative EA-230 in cardiac surgery patients. Cardiac surgery induces systemic inflammation and may impair renal function, affecting patient outcome. EA-230 exerted immunomodulatory and renoprotective effects in preclinica...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: van Groenendael, Roger, Beunders, Remi, Hemelaar, Pleun, Hofland, Jan, Morshuis, Wim J., van der Hoeven, Johannes G., Gerretsen, Jelle, Wensvoort, Gert, Kooistra, Emma J., Claassen, Wout J., Waanders, Denise, Lamberts, Maud G. A., Buijsse, Leonie S. E., Kox, Matthijs, van Eijk, Lucas T., Pickkers, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043513/
https://ncbi.nlm.nih.gov/pubmed/33591006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000004847
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