Neutralizing Autoantibodies to Type I IFNs in >10% of Patients with Severe COVID-19 Pneumonia Hospitalized in Madrid, Spain

BACKGROUND: In a recent study, autoantibodies neutralizing type I interferons (IFNs) were present in at least 10% of cases of critical COVID-19 pneumonia. These autoantibodies neutralized most type I IFNs but rarely IFN-beta. OBJECTIVES: We aimed to define the prevalence of autoantibodies neutralizi...

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Detalhes bibliográficos
Publicado no:J Clin Immunol
Main Authors: Troya, Jesús, Bastard, Paul, Planas-Serra, Laura, Ryan, Pablo, Ruiz, Montse, de Carranza, María, Torres, Juan, Martínez, Amalia, Abel, Laurent, Casanova, Jean-Laurent, Pujol, Aurora
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043439/
https://ncbi.nlm.nih.gov/pubmed/33851338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-021-01036-0
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