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Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines

[Image: see text] The novel coronavirus SARS-CoV-2, the cause of the COVID-19 pandemic, has inspired one of the most efficient vaccine development campaigns in human history. A key aspect of COVID-19 mRNA vaccines is the use of the modified nucleobase N1-methylpseudouridine (m1Ψ) to increase their e...

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Publicat a:ACS Cent Sci
Autors principals: Nance, Kellie D., Meier, Jordan L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043204/
https://ncbi.nlm.nih.gov/pubmed/34075344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.1c00197
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