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Selection of Optimal Bioinformatic Tools and Proper Reference for Reducing the Alignment Error in Targeted Sequencing Data

BACKGROUND: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis. METHODS: In this study, a framework is proposed to evaluate and improve the sequence mapping in targeted regions of the reference genome. In this...

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Detalhes bibliográficos
Publicado no:J Med Signals Sens
Main Authors: Nodehi, Hannane Mohammadi, Tabatabaiefar, Mohammad Amin, Sehhati, Mohammadreza
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043119/
https://ncbi.nlm.nih.gov/pubmed/34026589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/jmss.JMSS_7_20
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