PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity

BACKGROUND: Although using a blockade of programmed death-ligand 1 (PD-L1) to enhance T cell immune responses shows great promise in tumor immunotherapy, the immune-checkpoint inhibition strategy is limited for patients with solid tumors. The mechanism and efficacy of such immune-checkpoint inhibiti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Qu, Shuang, Jiao, Zichen, Lu, Geng, Yao, Bing, Wang, Ting, Rong, Weiwei, Xu, Jiahan, Fan, Ting, Sun, Xinlei, Yang, Rong, Wang, Jun, Yao, Yongzhong, Xu, Guifang, Yan, Xin, Wang, Tao, Liang, Hongwei, Zen, Ke
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042710/
https://ncbi.nlm.nih.gov/pubmed/33849634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02331-0
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