IFN-λ4 is associated with increased risk and earlier occurrence of several common infections in African children

Genetic polymorphisms within the IFNL3/IFNL4 genomic region, which encodes type III interferons, have been strongly associated with clearance of hepatitis C virus. We hypothesized that type III interferons might be important for the immune response to other pathogens as well. In a cohort of 914 Mali...

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Udgivet i:Genes Immun
Main Authors: Prokunina-Olsson, Ludmila, Morrison, Robert D., Obajemu, Adeola, Mahamar, Almahamoudou, Kim, Sungduk, Attaher, Oumar, Florez-Vargas, Oscar, Sidibe, Youssoufa, Onabajo, Olusegun O., Hutchinson, Amy A., Manning, Michelle, Kwan, Jennifer, Brand, Nathan, Dicko, Alassane, Fried, Michal, Albert, Paul S., Mbulaiteye, Sam M., Duffy, Patrick E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042471/
https://ncbi.nlm.nih.gov/pubmed/33850301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-021-00127-7
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