Packed red blood cells inhibit T-cell activation via ROS-dependent signaling pathways

Numerous observations indicate that red blood cells (RBCs) affect T-cell activation and proliferation. We have studied effects of packed RBCs (PRBCs) on T-cell receptor (TCR) signaling and the molecular mechanisms whereby (P)RBCs modulate T-cell activation. In line with previous reports, PRBCs atten...

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Vydáno v:J Biol Chem
Hlavní autoři: Gerner, Marlene C., Bileck, Andrea, Janker, Lukas, Ziegler, Liesa S., Öhlinger, Thomas, Raeven, Pierre, Müllner, Ernst W., Salzer, Ulrich, Gerner, Christopher, Schmetterer, Klaus G., Baron, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042437/
https://ncbi.nlm.nih.gov/pubmed/33676898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100487
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